Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pax3  paired box 3   (Synonyms: Pax-3, Splchl2)
Results	Reference
1	J:153597 Anderson C, Thorsteinsdottir S, Borycki AG, Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome. Development. 2009 Oct;136(20):3495-504
1	J:164695 Bush JR, Wevrick R, Loss of Necdin impairs myosin activation and delays cell polarization. Genesis. 2010 Sep;48(9):540-53
1*	J:141111 Chang CP, Stankunas K, Shang C, Kao SC, Twu KY, Cleary ML, Pbx1 functions in distinct regulatory networks to pattern the great arteries and cardiac outflow tract. Development. 2008 Nov;135(21):3577-86
1	J:105245 Chen AE, Ginty DD, Fan CM, Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins. Nature. 2005 Jan 20;433(7023):317-22
1	J:183920 Chen J, Lai F, Niswander L, The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15;26(8):803-15
1*	J:163733 Christova T, Mojtahedi G, Hamel PA, Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription. Int J Biochem Cell Biol. 2010 May;42(5):630-40
1	J:279139 Cibi DM, Mia MM, Guna Shekeran S, Yun LS, Sandireddy R, Gupta P, Hota M, Sun L, Ghosh S, Singh MK, Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate. Elife. 2019 Jun 26;8:e45418
1*	J:137690 Cooley MA, Kern CB, Fresco VM, Wessels A, Thompson RP, McQuinn TC, Twal WO, Mjaatvedt CH, Drake CJ, Argraves WS, Fibulin-1 is required for morphogenesis of neural crest-derived structures. Dev Biol. 2008 Jul 15;319(2):336-45
1*	J:72300 Dottori M, Gross MK, Labosky P, Goulding M, The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate. Development. 2001 Nov;128(21):4127-38
1	J:159118 Fotopoulou S, Oikonomou N, Grigorieva E, Nikitopoulou I, Paparountas T, Thanassopoulou A, Zhao Z, Xu Y, Kontoyiannis DL, Remboutsika E, Aidinis V, ATX expression and LPA signalling are vital for the development of the nervous system. Dev Biol. 2010 Mar 15;339(2):451-64
1	J:202293 Gray JD, Kholmanskikh S, Castaldo BS, Hansler A, Chung H, Klotz B, Singh S, Brown AM, Ross ME, LRP6 exerts non-canonical effects on Wnt signaling during neural tube closure. Hum Mol Genet. 2013 Nov 1;22(21):4267-81
1	J:56498 Gross MK, Moran-Rivard L, Velasquez T, Nakatsu MN, Jagla K, Goulding M, Lbx1 is required for muscle precursor migration along a lateral pathway into the limb. Development. 2000 Jan;127(2):413-24
1	J:220655 Harmacek L, Watkins-Chow DE, Chen J, Jones KL, Pavan WJ, Salbaum JM, Niswander L, A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. Dev Neurobiol. 2014 May;74(5):483-97
1	J:333726 Keuls RA, Oh YS, Patel I, Parchem RJ, Post-transcriptional regulation in cranial neural crest cells expands developmental potential. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2212578120
1	J:316475 Keuls RA, Parchem RJ, Single-Cell Multiomic Approaches Reveal Diverse Labeling of the Nervous System by Common Cre-Drivers. Front Cell Neurosci. 2021;15:648570
1	J:213766 Kicheva A, Bollenbach T, Ribeiro A, Valle HP, Lovell-Badge R, Episkopou V, Briscoe J, Coordination of progenitor specification and growth in mouse and chick spinal cord. Science. 2014 Sep 26;345(6204):1254927
1*	J:82459 Laclef C, Hamard G, Demignon J, Souil E, Houbron C, Maire P, Altered myogenesis in Six1-deficient mice. Development. 2003 May;130(10):2239-52
1	J:95257 Lee CT, Li L, Takamoto N, Martin JF, Demayo FJ, Tsai MJ, Tsai SY, The nuclear orphan receptor COUP-TFII is required for limb and skeletal muscle development. Mol Cell Biol. 2004 Dec;24(24):10835-43
1*	J:278508 Magli A, Baik J, Pota P, Cordero CO, Kwak IY, Garry DJ, Love PE, Dynlacht BD, Perlingeiro RCR, Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification. Nat Commun. 2019 May 24;10(1):2316
1	J:315934 Manderfield LJ, Engleka KA, Aghajanian H, Gupta M, Yang S, Li L, Baggs JE, Hogenesch JB, Olson EN, Epstein JA, Pax3 and hippo signaling coordinate melanocyte gene expression in neural crest. Cell Rep. 2014 Dec 11;9(5):1885-1895
1	J:327414 Manivannan S, Mansfield C, Zhang X, Kodigepalli KM, Majumdar U, Garg V, Basu M, Single-cell transcriptomic profiling unveils dysregulation of cardiac progenitor cells and cardiomyocytes in a mouse model of maternal hyperglycemia. Commun Biol. 2022 Aug 15;5(1):820
1	J:121554 Martinelli DC, Fan CM, Gas1 extends the range of Hedgehog action by facilitating its signaling. Genes Dev. 2007 May 15;21(10):1231-43
1	J:99329 Martynoga B, Morrison H, Price DJ, Mason JO, Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis. Dev Biol. 2005 Jul 1;283(1):113-27
1	J:212088 Mayeuf-Louchart A, Lagha M, Danckaert A, Rocancourt D, Relaix F, Vincent SD, Buckingham M, Notch regulation of myogenic versus endothelial fates of cells that migrate from the somite to the limb. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8844-9
1	J:240081 Mayeuf-Louchart A, Montarras D, Bodin C, Kume T, Vincent SD, Buckingham M, Endothelial cell specification in the somite is compromised in Pax3-positive progenitors of Foxc1/2 conditional mutants, with loss of forelimb myogenesis. Development. 2016 Mar 01;143(5):872-9
1	J:202820 Moore S, Ribes V, Terriente J, Wilkinson D, Relaix F, Briscoe J, Distinct regulatory mechanisms act to establish and maintain Pax3 expression in the developing neural tube. PLoS Genet. 2013 Oct;9(10):e1003811
1	J:189708 Murdoch B, DelConte C, Garcia-Castro MI, Pax7 lineage contributions to the mammalian neural crest. PLoS One. 2012;7(7):e41089
1	J:239276 Ohayon D, Venteo S, Sonrier C, Lafon PA, Garces A, Valmier J, Rivat C, Topilko P, Carroll P, Pattyn A, Zeb family members and boundary cap cells underlie developmental plasticity of sensory nociceptive neurons. Dev Cell. 2015 May 04;33(3):343-50
1*	J:170532 Pan H, Gustafsson MK, Aruga J, Tiedken JJ, Chen JC, Emerson CP Jr, A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis. Dev Biol. 2011 Mar 1;351(1):120-7
1	J:282947 Poncet N, Halley PA, Lipina C, Gierlinski M, Dady A, Singer GA, Febrer M, Shi YB, Yamaguchi TP, Taylor PM, Storey KG, Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos. EMBO Rep. 2020 Jan 7;21(1):e48469
1	J:232202 Rolo A, Savery D, Escuin S, de Castro SC, Armer HE, Munro PM, Mole MA, Greene N, Copp AJ, Regulation of cell protrusions by small GTPases during fusion of the neural folds. Elife. 2016;5:e13273
1*	J:173396 Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, Held S, Reutter HM, Lane WS, Rafiq MA, Noor A, Ansar M,Devi AR, Sheffield VC, Slusarski DC, Vincent JB, Doherty DA, Hildebrandt F, Reiter JF, Jackson PK, Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13;145(4):513-28
1	J:119082 Schuster-Gossler K, Cordes R, Gossler A, Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):537-42
1*	J:117808 Shih HP, Gross MK, Kioussi C, Expression pattern of the homeodomain transcription factor Pitx2 during muscle development. Gene Expr Patterns. 2007 Feb;7(4):441-51
1	J:217080 Van Nostrand JL, Brady CA, Jung H, Fuentes DR, Kozak MM, Johnson TM, Lin CY, Lin CJ, Swiderski DL, Vogel H, Bernstein JA, Attie-Bitach T, Chang CP, Wysocka J, Martin DM, Attardi LD, Inappropriate p53 activation during development induces features of CHARGE syndrome. Nature. 2014 Oct 9;514(7521):228-32
1	J:228522 Yang SL, Yang M, Herrlinger S, Liang C, Lai F, Chen JF, MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation. Dev Biol. 2015 Dec 1;408(1):140-50
1	J:243987 Zalc A, Rattenbach R, Aurade F, Cadot B, Relaix F, Pax3 and Pax7 play essential safeguard functions against environmental stress-induced birth defects. Dev Cell. 2015 Apr 06;33(1):56-66
1*	J:325429 Zhou HM, Conway SJ, Pax3 Hypomorphs Reveal Hidden Pax7 Functional Genetic Compensation in Utero. J Dev Biol. 2022 May 17;10(2)